The present study aims to investigate the effect of carrot seed oil (Daucus carota) on surgery wound healing. The study was performed by 8 white New Zealand rabbits with the average weight of 1.5 kg. Then, two pairs of round wounds with a diameter of 7 mm were created on the two sides of the spinal column in the anterior and posterior sites with a distance of 3 cm from the midline. The research was done on four groups of two (each rabbit had eight wound). The wounds of the first group were considered as the control samples, and they received no treatment. The second group wounds were treated by eucerin (the case control); the third group wounds were treated by carrot seed oil (the experimental group); and the fourth group wounds were treated by phenytoin (the standard group). After the surgery, the wounds were investigated by a microscopic study every three days. The histopathology test was done by histological sections of the lesion sites on the days 4, 9, and 21, and the healing process was eva‎luated. According to the results of ANOVA, there was a significant difference (P˂0.05) between the groups on all the testing days (except the 21th day when the results of the phenytoin and carrot seed oil were the same (P=1)).The findings suggest that phenytoin group compared to another groups, has been the most effective treatment in healing and reduction of the wound area on all the testing days. The next effective treatment in wound healing was carrot seed oil that resulted in an acceptable improvement. This study suggests that due to containing phenolic compounds and antioxidant, antibacterial, and anti-inflammatory effects, carrot seed oil can accelerate the wound healing process.

10/18/2020 12:00:00 AM

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